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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2156-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2156-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Cullin 1 Rabbit mAb |
|---|---|
| Accession (Primary) | Q13616 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 90 kDa; Observed MW: 90 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; ICC/IF-1:100-1:200 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Cullin1 (CUL1) belongs to the cullin family proteins that are scaffold proteins for the Ring finger type E3 ligases. Human has seven cullin proteins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Cullin1 is the mammalian homolog of Cdc53 from yeast. CUL1 has been shown to mediate ubiquitin dependent degradation of p21 Waf1/Cip1, cyclin D and IκBα. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality. | |
Target Information: ( Q13616 ) | |
| Name | CUL1 |
| Gene ID | 8454 |
| Other Names | |
| CUL1; cullin-1; MGC149834; MGC149835 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
