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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2250-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ2250-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | PKR Rabbit mAb |
|---|---|
| Accession (Primary) | Q03963 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 58 kDa; Observed MW: 74 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IF-1:100-1:200; FC-1:50-1:100; IP-1:20-1:50 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Enables double-stranded RNA binding activity and protein kinase activity. Involved in several processes, including negative regulation of viral genome replication; regulation of hematopoietic stem cell differentiation; and regulation of intracellular signal transduction. Acts upstream of or within several processes, including endoplasmic reticulum unfolded protein response; protein phosphorylation; and translation. Predicted to be located in cytosol and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including brain; genitourinary system; mandible condylar process; sensory organ; and skeletal musculature. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; dystonia 33; and hepatitis B. Orthologous to human EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2). | |
Target Information: ( Q03963 ) | |
| Name | Eif2Ak2 |
| Gene ID | 19106 |
| Other Names | |
| PKR; PRKR; EIF2AK2; PPP1R83; Interferon-induced; double-stranded RNA-activated protein kinase | |
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ADMEbio Team
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ADMEbio Team
