| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2367-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2367-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | VE Cadherin Rabbit mAb |
|---|---|
| Accession (Primary) | P55284 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Mouse |
| Calculated MW | |
| Calculated MW: 88 kDa; Observed MW: 90-140 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; ICC/IF-1:500-1:1000; IP-1:50-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. | |
Target Information: ( P55284 ) | |
| Name | Cdh5 |
| Gene ID | 12562 |
| Other Names | |
| Cadherin 5; 7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225; 7B 4; 7B4 antigen; | |
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ADMEbio Team
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