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>   Home   >   Products   >   Primary Antibodies   >   MMP14 Rabbit mAb   

MMP14 Rabbit mAb

 
Catalog #
ABZ2422
Application
WB, IF, FC, IP, ICC, IHC-P
Uniprot Id
P50281
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of MMP14 in CHO-K1 lysates using MMP14 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using MMP14 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2422-100 2 weeks 100 µL $499.00
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ABZ2422-20 2 weeks 20 µL $149.00
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Product Overview

NameMMP14 Rabbit mAb
Accession (Primary)P50281
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 66 kDa; Observed MW: 66 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:100-1:200; FC-1:100-1:200; IP-1:20
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Target Information: ( P50281 )

NameMMP14
Gene ID4323
Other Names
MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1
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