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GCLM Rabbit mAb

 
Catalog #
ABZ2455
Application
WB, IP, IHC-P
Uniprot Id
P48507
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of GCLM in Hela, A549, HL-60, U251 lysates using GCLM antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human tonsil using GCLM antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2455-100 2 weeks 100 µL $499.00
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ABZ2455-20 2 weeks 20 µL $149.00
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Product Overview

NameGCLM Rabbit mAb
Accession (Primary)P48507
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 31 kDa; Observed MW: 31 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:50-1:100; IP-1:20
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

Target Information: ( P48507 )

NameGCLM
Gene ID2730
Other Names
GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit; GCSm-γ
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