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>   Home   >   Products   >   Primary Antibodies   >   HP1 alpha Rabbit mAb   

HP1 alpha Rabbit mAb

 
Catalog #
ABZ2481
Application
WB, IF, FC, IP, ICC, IHC-F, IHC-P
Uniprot Id
P45973
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of HP1 alpha in C6, PC-12 lysates using HP1 alpha antibody.
  • Western blot analysis of HP1 alpha in 3T3, Hela lysates using HP1 alpha antibody.
  • Immunocytochemistry analysis of HP1 alpha(green) in Hela using HP1 alpha antibody,and DAPI(blue)
  • Immunohistochemistry analysis of paraffin-embedded Human colon cancer using HP1 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2481-100 2 weeks 100 µL $499.00
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ABZ2481-20 2 weeks 20 µL $149.00
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Product Overview

NameHP1 alpha Rabbit mAb
Accession (Primary)P45973
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 22 kDa; Observed MW: 22 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-P-1:200-1:1000; ICC/IF-1:100-1:200; FC-1:10-1:100; IP-1:10-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Target Information: ( P45973 )

NameCBX5
Gene ID23468
Other Names
CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha; Antigen p25; CBX5; CBX5_HUMAN;
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