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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2518-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2518-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | MLH1 Rabbit mAb |
|---|---|
| Accession (Primary) | P40692 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 85 kDa; Observed MW: 85 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:2000; IHC-1:20-1:50; IF-1:20-1:50; IF-1:20; IP-1:20 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. | |
Target Information: ( P40692 ) | |
| Name | MLH1 |
| Gene ID | 4292 |
| Other Names | |
| MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1 | |
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ADMEbio Team
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