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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2821-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2821-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | AF10 Rabbit mAb |
|---|---|
| Accession (Primary) | P55197 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 113 kDa; Observed MW: 140 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IHC-P-1:200-1:1000; FC-1:200-1:500 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302). | |
Target Information: ( P55197 ) | |
| Name | MLLT10 |
| Gene ID | 8028 |
| Other Names | |
| MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein; AF 10; AF10; AF10_HUMAN; | |
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ADMEbio Team
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ADMEbio Team
