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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2831-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2831-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Angiotensin Converting Enzyme 1 Rabbit mAb |
|---|---|
| Accession (Primary) | P09470 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Mouse, Rat |
| Calculated MW | |
| Calculated MW: 151 kDa; Observed MW: 180 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IHC-1:200-1:500 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Angiotensin I Converting Enzyme (ACE) is a transmembrane zinc metallopeptidase that hydrolyzes peptide chains by removing the dipeptide from the C-terminus. ACE is a key component of the renin-angiotensin system (RAS), which plays an important role in blood pressure homeostasis through the production of the vasoconstrictor peptide angiotensin II. ACE also plays a role in fertility, immunity, hematopoiesis, and diseases such as obesity, fibrosis, and Alzheimer's disease dementia. ACE is relevant to immune regulation in that endogenous ACE has been detected in a variety of immune cell populations including macrophages and neutrophils, and its overexpression results in enhanced bactericidal and antitumor responses independent of angiotensin II. | |
Target Information: ( P09470 ) | |
| Name | Ace |
| Gene ID | 11421 |
| Other Names | |
| ACE; CD143; Dcp1; Dipeptidyl carboxypeptidase I; Kininase II | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
