| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2898-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2898-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | CLPTM1 Rabbit mAb |
|---|---|
| Accession (Primary) | O96005 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 76 kDa; Observed MW: 90 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IP-1:20 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one. | |
Target Information: ( O96005 ) | |
| Name | CLPTM1 |
| Gene ID | 1209 |
| Other Names | |
| Cleft lip and palate associated transmembrane protein 1; Cleft lip and palate transmembrane protein 1; CLPT1_HUMAN; | |
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ADMEbio Team
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ADMEbio Team