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>   Home   >   Products   >   Primary Antibodies   >   DTYMK Rabbit mAb   

DTYMK Rabbit mAb

 
Catalog #
ABZ3286
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
P23919
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of DTYMK in Hela, Ramos lysates using DTYMK antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human tonsil using DTYMK antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3286-100 2 weeks 100 µL $499.00
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ABZ3286-20 2 weeks 20 µL $149.00
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Product Overview

NameDTYMK Rabbit mAb
Accession (Primary)P23919
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 24 kDa; Observed MW: 24 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:100-1:200; ICC/IF-1:100-1:200; FC-1:200-1:1000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
DTYMK (deoxythymidylate kinase (thymidylate kinase)), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

Target Information: ( P23919 )

NameDTYMK
Gene ID1841
Other Names
CDC8; TMPK; TYMK; PP3731
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