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ICAM3 Rabbit mAb

 
Catalog #
ABZ3314
Application
WB, IF, ICC, IHC-P
Uniprot Id
P32942
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of ICAM3 in Hela, A549, HL-60, U2OS, C6 lysates using ICAM3 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human tonsil using ICAM3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3314-100 2 weeks 100 µL $499.00
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ABZ3314-20 2 weeks 20 µL $149.00
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Product Overview

NameICAM3 Rabbit mAb
Accession (Primary)P32942
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 60 kDa; Observed MW: 110-160 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:200-1:1000; ICC/IF-1:100-1:200
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The intercellular adhesion molecule (ICAM) family is a subfamily of immunoglobulin superfamily with five known ICAM family members (ICAM1 to ICAM5) which play a role in inflammation, immune responses, and intracellular signaling (PMID: 23287428; 29477378). ICAM3, also known as CD50, is a type I transmembrane glycoprotein that contains five C2-type immunoglobulin-like domains in its extracellular region, a single transmembrane segment, and a C-terminus cytoplasmic tail. ICAM3 is selectively expressed on leukocytes (PMID: 1730916; 8132828). It is the primary ligand for LFA-1 and is involved in various immune processes, including T-cell activation, and macrophage recognition of apoptotic cells (PMID: 11812993; 23775590).

Target Information: ( P32942 )

NameICAM3
Gene ID3385
Other Names
CD50; ICAM-3; CDw50; ICAM-R; Intercellular adhesion molecule 3
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