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KIFAP3 Rabbit mAb

 
Catalog #
ABZ3323
Application
WB, IHC-P
Uniprot Id
Q92845
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of KIFAP3 in A549, HL-60, C6 lysates using KIFAP3 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KIFAP3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3323-100 2 weeks 100 µL $499.00
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ABZ3323-20 2 weeks 20 µL $149.00
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Product Overview

NameKIFAP3 Rabbit mAb
Accession (Primary)Q92845
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 91 kDa; Observed MW: 91 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:200-1:500
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

Target Information: ( Q92845 )

NameKIFAP3
Gene ID22920
Other Names
KAP3; KIF3AP; Kifap3; Kinesin associated protein 3; SMAP
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