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>   Home   >   Products   >   Primary Antibodies   >   Rad21 Rabbit mAb   

Rad21 Rabbit mAb

 
Catalog #
ABZ3358
Application
WB, IF, FC, IP, ICC, IHC-P
Uniprot Id
O60216
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Immunocytochemistry analysis of Rad21 (green) in Hela using Rad21 antibody,and DAPI(blue).
  • Western blot analysis of Rad21 in Hela, CHO-K1, Ramos lysates using Rad21 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Rad21 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3358-100 2 weeks 100 µL $499.00
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ABZ3358-20 2 weeks 20 µL $149.00
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Product Overview

NameRad21 Rabbit mAb
Accession (Primary)O60216
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 72 kDa; Observed MW: 130 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:50-1:100; IF-1:50-1:200
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

Target Information: ( O60216 )

NameRAD21
Gene ID5885
Other Names
RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21
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