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DAPK3 Rabbit mAb

 
Catalog #
ABZ3386
Application
WB
Uniprot Id
O43293
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of ZIP Kinase in Hela, A549, MCF-7, U251 lysates using DAP kinase 3 antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3386-100 2 weeks 100 µL $499.00
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ABZ3386-20 2 weeks 20 µL $149.00
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Product Overview

NameDAPK3 Rabbit mAb
Accession (Primary)O43293
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 53 kDa; Observed MW: 53 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
DAPK3, also named as ZIPK and Dlk, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. The calculated molecular weight of DAPK3 is 52 kDa. This antibody can recognize the 37 kDa isoform of target. ZIP kinase is a Serine/threonine kinase which acts as a positive regulator of apoptosis. ZIP kinasephosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. ZIP kinase regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. It catalyze the reaction: ATP + a protein = ADP + a phosphoprotein.

Target Information: ( O43293 )

NameDAPK3
Gene ID1613
Other Names
ZIP-kinase; DAPK3; ZIPK; Death-associated protein kinase 3; DAP kinase 3; DAP-like kinase; Dlk; MYPT1 kinase; Zipper-interacting protein kinase;
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