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>   Home   >   Products   >   Primary Antibodies   >   DR5 Rabbit mAb   

DR5 Rabbit mAb

 
Catalog #
ABZ3513
Application
IHC-P
Uniprot Id
O14763
Reactivity
Human
Isotype
IgG
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3513-100 2 weeks 100 µL $499.00
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ABZ3513-20 2 weeks 20 µL $149.00
  • Datasheet
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Product Overview

NameDR5 Rabbit mAb
Accession (Primary)O14763
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
IHC-P-1:200-1:2000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Target Information: ( O14763 )

NameTNFRSF10B
Gene ID8795
Other Names
TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186; CD262; Death receptor 5; Tumor necrosis factor receptor superfamily member 10B; NF-related apoptosis-inducing ligand receptor 2 (TRAIL receptor 2; TRAIL-R2)
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