| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3550-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3550-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | HLA-DP Rabbit mAb |
|---|---|
| Accession (Primary) | P20036 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| IHC-1:100-1:200 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. | |
Target Information: ( P20036 ) | |
| Name | HLA-DPA1 |
| Gene ID | 3113 |
| Other Names | |
| DPA1; PLT1; HLADP; HLASB; HLA DPA1; major histocompatibility complex; class II; DP alpha 1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DP1A; DP(W3); DP(W4); HLA class II histocompatibility antigen DP alpha 1 chain; | |
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