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MUC1 Rabbit mAb

 
Catalog #
ABZ3703
Application
WB, IHC-P
Uniprot Id
P15941
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of MUC1 in MCF-7, T4-7D lysates using MUC1 antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3703-100 2 weeks 100 µL $499.00
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ABZ3703-20 2 weeks 20 µL $149.00
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Product Overview

NameMUC1 Rabbit mAb
Accession (Primary)P15941
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW:122 kDa;Observed MW: 122 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:500-1:2000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
MUC1 is a type I transmembrane glycoprotein expressed by various epithelial cells of the female reproductive tract, lung, breast, kidney, stomach, and pancreas. MUC1 is transcribed as a large precursor gene product, and upon translation, is cleaved in the endoplasmic reticulum, yielding two subunits: the large extracellular N-terminal subunit (MUC1-N, about 120-200 kDa) and the small cytoplasmic C-terminal subunit (MUC1-C, about 23-30 kDa). Among the known mucins, MUC1 is best studied and plays crucial roles in regulating many cellular properties, including cell proliferation, apoptosis, adhesion, and invasion. MUC1 is overexpressed in a wide range of human epithelial malignancies. This antibody was raised against the C-terminal region of human MUC1, thus it recognizes the 23-30 kDa cytoplasmic MUC1.

Target Information: ( P15941 )

NameMUC1
Gene ID4582
Other Names
CD227; MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated ep
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