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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3756-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3756-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Munc 13-4 Rabbit mAb |
|---|---|
| Accession (Primary) | Q70J99 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse |
| Calculated MW | |
| Calculated MW:123 kDa;Observed MW: 123 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; FC-1:50-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells. | |
Target Information: ( Q70J99 ) | |
| Name | UNC13D |
| Gene ID | 201294 |
| Other Names | |
| FHL3; HLH3; HPLH3; Munc13-4; UNC13D; FHL 3; FHL3; FLJ00067; | |
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ADMEbio Team
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ADMEbio Team
