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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3790-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3790-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Cleaved C-terminal GSDMD Rabbit mAb |
|---|---|
| Accession (Primary) | Q9D8T2 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Mouse |
| Calculated MW | |
| Calculated MW: 22 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Gasdermin-D，Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:26375003, PubMed:26375259, PubMed:27281216). | |
Target Information: ( Q9D8T2 ) | |
| Name | GSDMD |
| Gene ID | 69146 |
| Other Names | |
| GSDMD,DFNA5L ,GSDMDC1,FKSG10,Gasdermin-D,Gasdermin domain-containing protein 1 | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
