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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3902-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3902-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Bax (2B12) Mouse mAb |
|---|---|
| Accession (Primary) | Q07812 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Species Reactivity | |
| Reacts With | Human, Cat |
| Calculated MW | |
| Calculated MW: 21 kDa; Observed MW: 21 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis. | |
Target Information: ( Q07812 ) | |
| Name | BAX |
| Gene ID | 581 |
| Other Names | |
| Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
