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>   Home   >   Products   >   Primary Antibodies   >   ZAP70 (4B2) Mouse mAb   

ZAP70 (4B2) Mouse mAb

 
Catalog #
ABZ3965
Application
WB, IP
Uniprot Id
P43403
Reactivity
Human
Isotype
IgG2b
 
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  • Western blot analysis of ZAP70 in CEM and Jurkat lysates, negative in the Ramos lysates using ZAP70 antibody.
  • Immunoprecipitation analysis of ZAP70 (4B2) in Jurkat lysates (ZAP70 positive expression cell line)and Ramos lysates(ZAP70 negative expression cell line) using ZAP70 antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3965-100 2 weeks 100 µL $499.00
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ABZ3965-20 2 weeks 20 µL $149.00
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Product Overview

NameZAP70 (4B2) Mouse mAb
Accession (Primary)P43403
Host SpeciesMouse
ClonalityMonoclonal
IsotypeIgG2b
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 70 kDa; Observed MW: 70 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IP-1:20
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.

Target Information: ( P43403 )

NameZAP70
Gene ID7535
Other Names
ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase
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