| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3971-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3971-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | STAT1 (6C2) Mouse mAb |
|---|---|
| Accession (Primary) | P42224 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Species Reactivity | |
| Reacts With | Human, Cat |
| Calculated MW | |
| Calculated MW: 87 kDa; Observed MW: 91 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IP-1:20 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. | |
Target Information: ( P42224 ) | |
| Name | STAT1 |
| Gene ID | 6772 |
| Other Names | |
| CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91 | |
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