| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4164-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4164-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | CKMT1 (1A6) Mouse mAb |
|---|---|
| Accession (Primary) | P12532 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Species Reactivity | |
| Reacts With | Human, Mouse |
| Calculated MW | |
| Calculated MW: 47 kDa; Observed MW: 47 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Creatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. | |
Target Information: ( P12532 ) | |
| Name | CKMT1A |
| Gene ID | 1159 |
| Other Names | |
| CKMT; CKMT1; UMTCK; CKMT1A | |
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ADMEbio Team
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