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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4246-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4246-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | DR5 Mouse mAb |
|---|---|
| Accession (Primary) | O14763 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 48 kDa; Observed MW: 40,48 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. | |
Target Information: ( O14763 ) | |
| Name | TNFRSF10B |
| Gene ID | 8795 |
| Other Names | |
| TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186; CD262; Death receptor 5; Tumor necrosis factor receptor superfamily member 10B; NF-related apoptosis-inducing ligand receptor 2 (TRAIL receptor 2; TRAIL-R2) | |
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ADMEbio Team
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ADMEbio Team
