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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4330-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4330-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Cleaved-Caspase 6 p18 Rabbit pAb |
|---|---|
| Accession (Primary) | P55212 |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Rat |
| Calculated MW | |
| Calculated MW: 33 kDa; Observed MW: 20,35 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:2000; IHC-1:100-1:300; IF-1:50-1:200; ELISA-1:40000 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Cleaved | |
| Form | |
| Liquid | |
| Background | |
| Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. | |
Target Information: ( P55212 ) | |
| Name | CASP6 |
| Gene ID | 839 |
| Other Names | |
| CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
