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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4505-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4505-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Phospho-Leptin Receptor (Tyr1141) Rabbit pAb |
|---|---|
| Accession (Primary) | P48357 |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse |
| Calculated MW | |
| Calculated MW: 132 kDa; Observed MW: 132 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:2000; ELISA-1:5000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Phosphorylated | |
| Form | |
| Liquid | |
| Background | |
| On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity). | |
Target Information: ( P48357 ) | |
| Name | LEPR |
| Gene ID | 3953 |
| Other Names | |
| Leptin receptor; LEP-R; HuB219 OB receptor; OB-R; CD295; LEPR; DB; OBR | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
