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[KD]Nicastrin Rabbit mAb

Catalog #: ABZ4643
Application: WB
Uniprot Id: Q92542
Reactivity: Human, Mouse, Rat
Isotype: IgG

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Western blot analysis of Nicastrin in HT1080(WT) and Nicastrin-Knockdown HT1080(KD) using Nicastrin antibody.
Western blot analysis of Nicastrin in K562, rat Brain, 3T3, Hela lysates using Nicastrin antibody.

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	ABZ4643-20	2 weeks	20 µL	reduce add	$149.00	Add to Cart INQUIRE Select product before adding to cart

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KD]Nicastrin Rabbit mAb
Accession (Primary)	Q92542
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 78 kDa; Observed MW: 110-120 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
Target Information: ( Q92542 )
Name	NCSTN
Gene ID	23385
Other Names
APH2; Ncstn; NCT; Nicastrin; Anterior pharynx defective 2; APH 2; APH2;

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