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[KD]MLKL Rabbit mAb

Catalog #: ABZ4647
Application: WB, IF, ICC, IHC-P
Uniprot Id: Q8NB16
Reactivity: Human
Isotype: IgG

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Western blot analysis of MLKL in HeLa(WT) and MLKL-Knockdown HeLa(KD) using MLKL antibody.
Western blot analysis of MLKL in HUVEC，RAW264.7 lysates using MLKL antibody.
Immunohistochemistry analysis of paraffin-embedded Human colon using MLKL antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of MLKL in 3T3, SW480, Ramos and Hela lysates using MLKL antibody.
Western blot analysis of MLKL in HUVEC lysates using MLKL antibody

	Catalog #	Availability	Size	Quantity	Unit Price	Save For Later Wish List
	ABZ4647-100	2 weeks	100 µL	reduce add	$499.00	Add to Cart INQUIRE Select product before adding to cart
	ABZ4647-20	2 weeks	20 µL	reduce add	$149.00	Add to Cart INQUIRE Select product before adding to cart

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KD]MLKL Rabbit mAb
Accession (Primary)	Q8NB16
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human
Calculated MW
Calculated MW: 54 kDa; Observed MW: 54 kDa
Buffer System
1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-1:50-1:200; ICC/IF-1:100-1:200
Purification
Affinity Chromatography
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Target Information: ( Q8NB16 )
Name	MLKL
Gene ID	197259
Other Names
MLKL; hMLKL; 9130019I15Rik; FLJ34389; hMLKL;

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