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>   Home   >   Products   >   Primary Antibodies   >   [KO]Thyroid Transcription Factor 1 Rabbit mAb   

[KO]Thyroid Transcription Factor 1 Rabbit mAb

 
Catalog #
ABZ4678
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
P43699
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Thyroid Transcription Factor 1 in HeLa(WT) and Thyroid Transcription Factor 1-Knockout HeLa(KO) using Thyroid Transcription Factor 1 antibody.
  • Western blot analysis of TTF1 in rat brain lysates using Thyroid Transcription Factor 1 antibody.
  • Western blot analysis of TTF1 in 3T3 lysates using TTF1 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human lung cancer using TTF1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4678-100 2 weeks 100 µL $499.00
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ABZ4678-20 2 weeks 20 µL $149.00
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Product Overview

Name[KO]Thyroid Transcription Factor 1 Rabbit mAb
Accession (Primary)P43699
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 39 kDa; Observed MW: 39 kDa
Buffer System
1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:8000; IHC-1:100-1:2000; IF-1:50-1:200; FC-1:50-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer.

Target Information: ( P43699 )

NameNKX2-1
Gene ID7080
Other Names
NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1
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