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>   Home   >   Products   >   Primary Antibodies   >   [KO]Phospho-PKR (Thr451) Rabbit mAb   

[KO]Phospho-PKR (Thr451) Rabbit mAb

 
Catalog #
ABZ4724
Application
WB
Uniprot Id
P19525
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of Phospho-PKR (Thr451) in HeLa(WT) and Phospho-PKR (Thr451)-Knockout HeLa(KO) using Phospho-PKR (Thr451) antibody.
  • Western blot analysis of PKR (Phospho-Thr451) in Hela, Hela+CalyculinA lysates using Phospho-PKR (Thr451) antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4724-100 2 weeks 100 µL $499.00
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ABZ4724-20 2 weeks 20 µL $149.00
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Product Overview

Name[KO]Phospho-PKR (Thr451) Rabbit mAb
Accession (Primary)P19525
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 62 kDa; Observed MW: 74 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Phosphorylated
Form
Liquid
Background
PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

Target Information: ( P19525 )

NameEIF2AK2
Gene ID5610
Other Names
EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
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