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![[KD]Bcl 10 Rabbit mAb ABZ4734](http://img.admebio.com/products/SEAC100001/20260405/ABZ4734-KD.jpg)
![[KD]Bcl 10 Rabbit mAb ABZ4734](http://img.admebio.com/products/SEAC100001/20260405/ABZ4734-WB-1.jpg)
![[KD]Bcl 10 Rabbit mAb ABZ4734](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4734-KD.jpg)
![[KD]Bcl 10 Rabbit mAb ABZ4734](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4734-WB-1.jpg)
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4734-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ4734-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KD]Bcl 10 Rabbit mAb |
|---|---|
| Accession (Primary) | O95999 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 26 kDa; Observed MW: 26 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; ICC/IF-1:100-1:200 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. | |
Target Information: ( O95999 ) | |
| Name | BCL10 |
| Gene ID | 8915 |
| Other Names | |
| BCL10; CIPER; CLAP; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog | |
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