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![[KD]KDM2A Rabbit mAb ABZ4758](http://img.admebio.com/products/SEAC100001/20260405/ABZ4758-WB-1.jpg)
![[KD]KDM2A Rabbit mAb ABZ4758](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4758-WB-1.jpg)
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4758-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4758-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KD]KDM2A Rabbit mAb |
|---|---|
| Accession (Primary) | Q9Y2K7 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 133 kDa; Observed MW: 133 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IHC-P-1:100-1:200; ICC/IF-1:500-1:1000; IP-1:50-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. | |
Target Information: ( Q9Y2K7 ) | |
| Name | KDM2A |
| Gene ID | 22992 |
| Other Names | |
| FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA | |
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ADMEbio Team
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