| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4836-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4836-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | CDT2 Rabbit mAb |
|---|---|
| Accession (Primary) | Q9NZJ0 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 79 kDa; Observed MW: 91 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:50-1:100; FC-1:100-1:200 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). | |
Target Information: ( Q9NZJ0 ) | |
| Name | DTL |
| Gene ID | 51514 |
| Other Names | |
| CDW1; DCAF2; Dtl; L2DTL; RAMP | |
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ADMEbio Team
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ADMEbio Team