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Caveolin-1 Rabbit mAb

 
Catalog #
ABZ4910
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
Q03135
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Caveolin1 in A431 lysates using Caveolin 1 antibody.
  • Immunohistochemistry analysis of paraffin-embedded mouse lung using Caveolin1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Immunofluorescence analysis of Caveolin 1 in A431 using Caveolin1 antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4910-100 2 weeks 100 µL $499.00
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ABZ4910-20 2 weeks 20 µL $149.00
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Product Overview

NameCaveolin-1 Rabbit mAb
Accession (Primary)Q03135
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 20 kDa; Observed MW: 25 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:200-1:2000; ICC/IF-1:20-1:50; FC-1:20
Purification
Affinity Chromatography
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Target Information: ( Q03135 )

NameCAV1
Gene ID857
Other Names
CAV1; CAV; Caveolin-1; BSCL3; CAV; CAV1;
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