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>   Home   >   Products   >   Primary Antibodies   >   ER alpha Rabbit mAb   

ER alpha Rabbit mAb

 
Catalog #
ABZ4986
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
P03372
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of Estrogen Receptor α in MCF-7 lysates using Estrogen Receptor alpha antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Estrogen Receptor alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4986-100 2 weeks 100 µL $499.00
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ABZ4986-20 2 weeks 20 µL $149.00
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Product Overview

NameER alpha Rabbit mAb
Accession (Primary)P03372
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 66 kDa; Observed MW: 66 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC:1:100-1:200; ICC/IF-1:100-1:200; FC-1:20
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

Target Information: ( P03372 )

NameESR1
Gene ID2099
Other Names
Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ESR1; ESR; NR3A1
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