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>   Home   >   Products   >   Primary Antibodies   >   Fibrillarin Rabbit mAb   

Fibrillarin Rabbit mAb

 
Catalog #
ABZ5029
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
P22087
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Fibrillarin in HepG2 lysates using Fibrillarin antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human testis using Fibrillarin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Immunofluorescence analysis of Fibrillarin in Hela using Fibrillarin antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ5029-100 2 weeks 100 µL $499.00
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ABZ5029-20 2 weeks 20 µL $149.00
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Product Overview

NameFibrillarin Rabbit mAb
Accession (Primary)P22087
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 34 kDa; Observed MW: 34 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; ICC/IF-1:500-1:5000; FC-1:10-1:100; IHC-1:50-1:100
Purification
Affinity Chromatography
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.

Target Information: ( P22087 )

NameFBL
Gene ID2091
Other Names
FIB; FLRN; Nop1; RNU3IP1; Fibrillarin/U3 RNP; 34 kD nucleolar scleroderma antigen; 34 kDa nucleolar scleroderma antigen; Fbl;
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