| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ5084-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ5084-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Thymidine Kinase 1/TK1 Rabbit mAb |
|---|---|
| Accession (Primary) | P04183 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 25 kDa; Observed MW: 25 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IHC-P-1:100-1:200; FC-1:100-1:200; IP-1:20 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. | |
Target Information: ( P04183 ) | |
| Name | TK1 |
| Gene ID | 7083 |
| Other Names | |
| TK1; Thymidine kinase 1; EC 2.7.1.21; KITH; TK-1; cytosolic | |
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ADMEbio Team
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ADMEbio Team