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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ5159-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ5159-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Securin Rabbit mAb |
|---|---|
| Accession (Primary) | O95997 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 22 kDa; Observed MW: 28 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:200; ICC/IF-1:20-1:50; FC-1:20-1:50 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. | |
Target Information: ( O95997 ) | |
| Name | PTTG1 |
| Gene ID | 9232 |
| Other Names | |
| PTTG1; EAP1; PTTG; TUTR1; Securin; Esp1-associated protein; Pituitary tumor-transforming gene 1 protein; Tumor-transforming protein 1; hPTTG | |
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ADMEbio Team
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ADMEbio Team
