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>   Home   >   Products   >   Primary Antibodies   >   VDAC1/Porin Rabbit mAb   

VDAC1/Porin Rabbit mAb

 
Catalog #
ABZ5247
Application
WB, IF, ICC, IHC-P
Uniprot Id
P21796
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Calreticulin in (1) HepG2 lysates; (2) Jurkat lysates using VDAC1 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot analysis of VDAC1 in C2C12, THP-1, 3T3, Jurakt and Hela lysates using VDAC1 antibody
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ5247-100 2 weeks 100 µL $499.00
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ABZ5247-20 2 weeks 20 µL $149.00
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Product Overview

NameVDAC1/Porin Rabbit mAb
Accession (Primary)P21796
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 31 kDa; Observed MW: 31 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:100-1:200; ICC/IF-1:500-1:1000
Purification
Affinity Chromatography
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.

Target Information: ( P21796 )

NameVDAC1
Gene ID7416
Other Names
VDAC1; VDAC; PORIN; Non-selective voltage-gated ion channel VDAC1;
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