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![[KD]LRP1 Rabbit mAb ABZ5307](http://img.admebio.com/products/SEAC100001/20260405/ABZ5307-WB-1.jpg)
![[KD]LRP1 Rabbit mAb ABZ5307](http://img.admebio.com/products/SEAC100001/20260405/ABZ5307-IHC-2.jpg)
![[KD]LRP1 Rabbit mAb ABZ5307](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ5307-WB-1.jpg)
![[KD]LRP1 Rabbit mAb ABZ5307](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ5307-IHC-2.jpg)
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ5307-100 | 2 weeks | 100 µL | $499.00 |
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|
||
| ABZ5307-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KD]LRP1 Rabbit mAb |
|---|---|
| Accession (Primary) | Q07954 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 505 kDa; Observed MW: 85 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:50-1:100; FC-1:50-1:100; IP-1:20-1:50 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. | |
Target Information: ( Q07954 ) | |
| Name | LRP1 |
| Gene ID | 4035 |
| Other Names | |
| APR; KPA; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R; IGFBP-3R; IGFBP3R1 | |
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