| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ5316-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ5316-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KO]PARK7/DJ1 Rabbit mAb |
|---|---|
| Accession (Primary) | Q99497 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 20 kDa; Observed MW: 24 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:200-1:1000; ICC/IF-1:50-1:500; FC-1:20-1:50; IP-1:20 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress. | |
Target Information: ( Q99497 ) | |
| Name | PARK7 |
| Gene ID | 11315 |
| Other Names | |
| CAP1; DJ-1; DJ1; PARK7; Protein DJ-1; Oncogene DJ1; Parkinson disease protein 7 | |
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ADMEbio Team
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ADMEbio Team