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>   Home   >   Products   >   Primary Antibodies   >   APE1 Rabbit mAb   

APE1 Rabbit mAb

 
Catalog #
ABZ2605
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
P27695
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of APE1 in K562, C6, 3T3, Hela lysates using APE1 antibody.
  • Immunocytochemistry analysis of APE1(green) in Hela using APE1 antibody,and DAPI(blue)
  • Immunohistochemistry analysis of paraffin-embedded Human tonsil using APE1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2605-100 2 weeks 100 µL $499.00
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ABZ2605-20 2 weeks 20 µL $149.00
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Product Overview

NameAPE1 Rabbit mAb
Accession (Primary)P27695
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 36 kDa; Observed MW: 36 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-P-1:200-1:2000; ICC/IF-1:100-1:200; FC-1:200-1:500
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway. Repair activities of Ape1 are stimulated by interaction with XRCC1, another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, proliferation and differentiation.

Target Information: ( P27695 )

NameAPEX1
Gene ID328
Other Names
APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1
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