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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3940-100 | 2 weeks | 100 µL | $499.00 |
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||
| ABZ3940-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | ATP Citrate Lyase (3D9) Mouse mAb |
|---|---|
| Accession (Primary) | P53396 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Species Reactivity | |
| Reacts With | Human, Mouse, Cat |
| Calculated MW | |
| Calculated MW: 121 kDa; Observed MW: 121 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IF-1:50-1:200; FC-1:50-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. | |
Target Information: ( P53396 ) | |
| Name | ACLY |
| Gene ID | 47 |
| Other Names | |
| ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
