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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0015-2 | 2 µg | $120.00 |
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| CYK0015-10 | 10 µg | $290.00 | ||||
| CYK0015-1 | 1 mg | $8,320.00 |
Product Overview | |
| Name | Acrp30 Mouse |
|---|---|
| Description | |
| Adiponectin Mouse Recombinant | |
| Accession (Primary) | Q60994 |
| Synonyms | |
| Acrp30, AdipoQ, GBP-28, APM-1, ACDC. | |
| Introduction | |
| Adiponectin is an important negative regulator in hematopoiesis and immune systems. It may be involved in ending inflammatory responses through its inhibitory functions. Inhibits endothelial nf-kappa-b signaling through a camp-dependent pathway. Inhibits tnf-alpha- induced expression of endothelial adhesion molecules. Involved in the control of fat metabolism and insulin sensitivity. | |
| Source | |
| HEK293 (Human embryonic kidney cell line). | |
| Formulation | |
| Filtered (0.4 µm) and lyophilized from 0.5 mg/ml in 0.05M PBS buffer,0.075M NaCl, pH7.4. | |
| Stability | |
| Store lyophilized APM-1 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 98.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYMYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN DYKDDDDK . | |
| Biological Activity | |
| Full-length adiponectin activates AMP-activated protein kinase in hepatocyte. Adiponectin also activates AMPK in HepG2 human hepatocytes at the concentration of 1.0 µg/ml. An in vitro gluconeogenesis assay which was performed in primary rat hepatocytes showed the murine adiponectin derived from mammalian cells can inhibit glucose production. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Acrp30 Mouse in sterile 18M-cm H 2 O at 0.5mg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| Acrp30 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q60994 ) | |
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ADMEbio Team
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