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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0001-2 | 2 µg | $120.00 |
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| GRF0001-10 | 10 µg | $290.00 | ||||
| GRF0001-1 | 1 mg | $4,320.00 |
Product Overview | |
| Name | Activin A Human |
|---|---|
| Description | |
| Activin A Human Recombinant | |
| Accession (Primary) | P08476 |
| Synonyms | |
| Inhba, Inhibin beta A, FSH releasing protein. | |
| Introduction | |
| Activins are homodimers or heterodimers of the different ? subunit isoforms, part of the TGF? family. Mature Activin A has two 116 amino acids residues betaA subunits (bA-bA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. | |
| Source | |
| Nicotiana benthamiana plant | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from 1mg/ml solution in Tris HCl 0.05M buffer at pH 7.4. | |
| Stability | |
| Lyophilized Activin A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Activin A should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| HHHHHHGLEC DGKVNICCKK QFFVSFKDIG WNDWIIAPSG YHANYCEGEC PSHIAGTSGS SLSFHSTVIN HYRMRGHSPF ANLKSCCVPT KLRPMSMLYY DDGQNIIKKD IQNMIVEECG CS | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Activin A in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| Activin A Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P08476 ) | |
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ADMEbio Team
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