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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABP0002-200 | 200 µl | $1,180.00 |
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| ABP0002-400 | 400 µl | $2,000.00 | ||||
| ABP0002-600 | 600 µl | $1,920.00 |
Product Overview | |
| Name | Anthrax LF Antibody |
|---|---|
| Description | |
| Anthrax LF Polyclonal Antibody | |
| Immunogen | |
| Anthrax PA Antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 240-254 of the Anthrax PA protein (~83 kD). Anthrax PA Antibody is cleaved from the 83 kDa form to the 63 kDa form at amino acids 164-167. Thus the Anthrax PA antibody (made against amino acids 250-250) should recognize both the 83 kDa and 63 kDa PA forms, but not the 20 kDa cleavage fragment. | |
| Introduction | |
| Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2). | |
| Formulation | |
| 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. | |
| Stability | |
| Store at 4°C, stable for 6 months. For long-term storage, store at -20°C. | |
| Applications | |
| This polyclonal antibody can be used for detection of Anthrax PA protein in western blot, 1:1000. | |
| Type | |
| Rabbit Anti Human Polyclonal Antibody. | |
| Precautions | |
| Anthrax LF Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
