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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4155-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ4155-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Aurora A (2E3) Mouse mAb |
|---|---|
| Accession (Primary) | O14965 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Species Reactivity | |
| Reacts With | Human, Cat |
| Calculated MW | |
| Calculated MW: 46 kDa; Observed MW: 46 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IF-1:50-1:200 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. | |
Target Information: ( O14965 ) | |
| Name | AURKA |
| Gene ID | 6790 |
| Other Names | |
| AIK; ARK1; AYK1; Aurora-A; Aurora-family kinase 1; Aurora-related kinase 1; Aurora/IPL1-related kinase 1; BTAK; Breast-tumor-amplified kinase; EC 2.7.11.1; IAK1; Ipl1- and aurora-related kinase 1; STK15; STK6; Serine/threonine kinase 15; Serine/threonine | |
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ADMEbio Team
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ADMEbio Team
