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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| NTR0005-2 | 2 µg | $120.00 |
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| NTR0005-10 | 10 µg | $290.00 | ||||
| NTR0005-1 | 1 mg | $7,488.00 |
Product Overview | |
| Name | BDNF Human |
|---|---|
| Description | |
| Brain-Derived Neurotrophic Factor Human Recombinant | |
| Accession (Primary) | P23560 |
| Synonyms | |
| Brain-Derived Neurotrophic Factor, BDNF, MGC34632, Abrineurin, ANON2, BULN2. | |
| Introduction | |
| BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. BDNF is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. | |
| Source | |
| HEK293 Cells. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| BDNF filtered (0.4 µm) and lyophilized from 0.5mg/ml in PBS. | |
| Stability | |
| Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| APMKEANIRG QGGLAYPGVR THGTLESVNG PKAGSRGLTS LADTFEHVIE ELLDEDQKVR PNEENNKDAD LYTSRVMLSS QVPLEPPLLF LLEEYKNYLD AANMSMRVRR HHHHHH . | |
| Solubility | |
| It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. | |
| Precautions | |
| BDNF Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P23560 ) | |
Background |
Final Thoughts Although more research is needed on the safety and effectiveness of BDNF human recombinant, trials suggest that this laboratory-produced protein may be effective in managing and treating several neurological and psychiatric disorders. It's important for experts to stay up to date on the latest developments and research to learn more about potential risks and benefits. |
References |
Title :Generation of Neurons with Improved Cell Survival and Phenotype Maintenance Using a Degradation-Resistant Nurr1 Mutant † ‡ Publication :Article first published online: 11 JUN 2009 DOI: 10.1002/stem.146 Copyright © 2009 AlphaMed Press. Link : BDNF prospec publication |
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ADMEbio Team
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