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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CHK0006-1 | 1 µg | $120.00 |
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| CHK0006-5 | 5 µg | $290.00 | ||||
| CHK0006-50 | 50 µg | $1,920.00 |
Product Overview | |
| Name | BRAK Human, His |
|---|---|
| Description | |
| BRAK Human Recombinant (CXCL14), His-Tag | |
| Accession (Primary) | O95715 |
| Synonyms | |
| C-X-C motif chemokine 14, B-cell and monocyte-activating chemokine, Chemokine BRAK, Kidney-expressed chemokine CXC, MIP-2G, Small-inducible cytokine B14, Cxcl14, Bmac, Kec, Ks1, Mip2g, Scyb14, BRAK, NJAC, AI414372, bolekine, MIP2gamma, 1110031L23Rik, 1200006I23Rik. | |
| Introduction | |
| CXCL14 is involved in immunoregulatory and inflammatory processes. BRAK protein is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. CXCL14 displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. CXCL14 is involved in the homeostasis of monocyte-derived macrophages. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| CXCL14 was lyophilized from a 0.2 µm filtered concentrated solution in 20mM PB, pH 7.4 and 500mM NaCl. | |
| Stability | |
| Lyophilized CXCL14 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL14 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE. | |
| Biological Activity | |
| The ED 50 of CXCL14 as determined by its ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized CXCL14 in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| BRAK Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O95715 ) | |
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ADMEbio Team
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ADMEbio Team
